Protein Conformational Flexibility Analysis with Noisy Data (2007)
Protein conformational changes play a critical role in biological functions such as ligand-protein and protein-protein interactions. Due to the noise in structural data, determining salient...
Characterizing Protein Conformation Space (2007)
Nigham, Anshul, Hsu, David, Latombe, Jean-Claude
In this work, we propose a radical approach for exploring the space of all possible protein structures. We present techniques to explore the clash-free conformation space, which comprises all protein...
Characterizing Protein Conformation Space (2007)
Nigham, Anshul, Hsu, David, Latombe, Jean-Claude
In this work, we propose a radical approach for exploring the space of all possible protein structures. We present techniques to explore the clash-free conformation space, which comprises all protein...
pFlexAna: detecting conformational changes in remotely related proteins
Nigham, Anshul, Tucker-Kellogg, Lisa, Mihalek, Ivana, Verma, Chandra, Hsu, David
The pFlexAna (protein flexibility analyzer) web server detects and displays conformational changes in remotely related proteins, without relying on sequence homology. To do so, it first applies a...